GadoSpin™ F

GadoSpin F is a unique MRI agent developed for atherosclerosis imaging. It contains a hydrophobic targeting moiety for high protein binding affinity. The agent accumulates in atherosclerotic plaques and enables T₁-weighted visualization of plaque burden.

The unique amphiphilic agent for plaque imaging:

• Contains a hydrophobic targeting moiety
• Accumulates in atherosclerotic plaques
• Leads to significant T₁ positive enhancement in the vascular system

Alternatively, benefit from GadoSpin F:

• For efficient lymph node and inflammation imaging based on its selective enrichment
• By easily performing an additional angiography scan during GadoSpin F's extended blood pool phase

Physico-chemical properties and structure

Schematic diagram of GadoSpin F:

Relaxivity (37 °C, 1.5 T)

r₁ = 18 L mmol^-1 s^-1
r₂ = 31 L mmol^-1 s^-1

r₁ = 15 L mmol^-1 s^-1
r₂ = 20 L mmol^-1 s^-1

~1,300 g mol^-1