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Scintica

GadoSpin™ D

GadoSpin™ D

$649.60 USD
$649.60 USD
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GadoSpin D is a unique dendritic MRI agent for studying blood vessel integrity and angiogenesis in tumors and inflamed tissues via dynamic contrast-enhanced (DCE) MRI. It contains 24 gadolinium ions in a globular structure.

The unique dendritic MRI agent:

  • Has an intermediate molecular weight optimized for vascular studies
  • Stays confined within intact vasculature
  • Passes through fenestrated blood vessel in tumors and inflamed tissue

Apply GadoSpin D to effectively:

  • Quantitate angiogenesis and investigate vascular abnormalities in tumors and inflammation with ease
  • Monitor therapeutic efficacy
  • Use its blood pool effect for MR angiography as an alternative to GadoSpin P
Physico-chemical properties and structure

Relaxivity (37 °C, 1.5T)

In plasma:

r1 = 19 L mmol-1 s-1
r2 = 29 L mmol-1 s-1

In water:

r1 = 17 L mmol-1 s-1
r2 = 22 L mmol-1 s-1

Molecular weight:

~17,000 g mol-1


Schematic diagram of GadoSpin D:

 

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