Small Animal Whole Body Photoacoustic and Fluorescence Molecular Imaging Platform.
The TriTom imaging platform utilizes photoacoustic and fluorescence tomographies (PAFT) to enable high-resolution (up to 160 µm) non-invasive in vivo whole-body imaging in small animal models. With the ability to use multiple excitation wavelengths per scan, the multi-modality system can simultaneously acquire photoacoustic and fluorescence data in large volumes (> 25 cm3) allowing for spectroscopic molecular analysis within the region of interest. In addition to 3D molecular maps, the TriTom enables spatially-resolved assessment of physiologic parameters in vivo, such as volumetric blood content and oxygenation without the need for contrast agents.
The TriTom also provides quantitative imaging for a wide range of fluorophores and other types of molecular probes excited between 460 nm and 1320 nm. With such versatile imaging capabilities, the state-of-the-art TriTom system is ideally suited for a wide range of preclinical applications including cancer, toxicology, developmental biology, tissue engineering and regeneration, neuroscience, cardiovascular imaging, as well as in the development of drugs, therapies, and optical and fluorescent imaging probes.
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